The prevalence and relevance of patch testing with textile dyes. (12th December 2022)

• Record Type: Journal Article
• Authors: Nijman, Lars; Rustemeyer, Thomas; Franken, Sylvie M.; Ipenburg, Norbertus A.
• Is Part Of: Contact dermatitis. Volume 88:Number 3(2023)
• Page Start: 220
• Page End: 229
• Publication Date: 2022-12-12
• Subjects: contact allergy -- patch testing -- PPD -- PPDallergic contact dermatitis -- textile dye mix -- textile dyes; Contact dermatitis -- Periodicals; 616.51
• DOI: 10.1111/cod.14260
• Languages: English
• ISSNs: 0105-1873

Abstract

Abstract: Background: Textile dye mix (TDM) is included in the European baseline series (EBS), but it is unknown if TDM identifies all patients with a textile dye allergy. Objectives: To assess the added value of performing patch testing with individual textile dyes in addition to TDM. Methods: Two hundred and nine patients suspected to have a contact allergy to textile dyes were patch tested between January 2015 and December 2021 with the EBS, as well as an individual textile dye test series containing textile dyes part of TDM (TDM‐dyes) and outside the scope of TDM (non‐TDM dyes). Results: Fifty‐four patients (25.8%) tested positive for TDM or an individual textile dye. Disperse Orange 3 (9.6%) followed by Disperse Blue 106 (4.8%) were the most common individual textile dyes causing a positive patch test reaction. Of the 54 dye positive patients, 28 (51.9%) had a clinically relevant reaction. No clinically relevant reactions were seen in patients that solely tested positive for non‐TDM dyes. Conclusions: It is beneficial to test individual textile dyes in addition to TDM in patients suspected of having a textile dye allergy. Otherwise, 46.3% of the dye positive patients and 35.7% of the patients with a clinically relevant reaction would have been missed. Abstract : Fifty‐four (25.8%) out of 209 patients tested positive to TDM or an individual textile dye. Of the 54 dye positive patients, 28 (51.9%) had a clinically relevant reaction. It is beneficial to test individual textile dyes in addition to TDM in patients suspected of having a textile dye allergy.