Scalable copper‐catalyzed preparation of imidazopyridinones from iodopyridinyl ureas. (7th November 2022) - Rugg, Kyle W.
Abstract: The efficient copper‐catalyzed construction of imidazopyridinones is described. Beginning from iodopyridinyl ureas, Ullmann coupling provides imidazopyridinones in good yield. Manufacturing by this process is described on 473 kg scale; the scope and limitations of substrates is also detailed. Abstract : The efficient copper‐catalyzed construction of imidazopyridinones is described. Beginning from iodopyridinyl ureas, Ullmann coupling provides imidazopyridinones in good yield. Manufacturing by this process is described on 473 kg scale; the scope and limitations of substrates is also detailed.