Is perioperative fast-track management the future of proximal aortic repair?. (20th December 2022)

• Record Type: Journal Article
• Authors: Haunschild, Josephina; van Kampen, Antonia; Misfeld, Martin; Von Aspern, Konstantin; Ender, Jörg; Zakhary, Waseem; Borger, Michael A; Etz, Christian D
• Is Part Of: European journal of cardio-thoracic surgery. Volume 63:Number 2(2023)
• Publication Date: 2022-12-20
• Subjects: Modified Bentall procedure -- Aortic root aneurysm -- Aortic valve dysfunction -- Fast-track concept -- Intermediate care; Heart -- Surgery -- Periodicals; Chest -- Surgery -- Periodicals; 617.54
• DOI: 10.1093/ejcts/ezac578
• Languages: English
• ISSNs: 1010-7940

Abstract

Abstract: OBJECTIVES: The Bentall procedure is the gold standard for patients with combined aortic root dilation and valve dysfunction. Over the past decade, fast-track (FT) perioperative anaesthetic management protocols have progressively evolved. We reviewed our results for selected patients undergoing Bentall surgery under an FT protocol. METHODS: We retrospectively analysed a consecutive cohort of patients who underwent elective Bentall procedures at our institution between 2000 and 2018. Complex aortic root repair (i.e. David and Ross procedure, redo surgery, major concomitant procedures, emergency repair for acute dissections) was excluded. Patients who underwent conventional perioperative treatment and those treated according to our institutional FT concept were compared following 1:1 propensity score matching. RESULTS: Of 772 patients who fit the in- and exclusion criteria, 565 were treated conventionally post-surgery, while 207 were treated using the FT protocol. Propensity score matching resulted in 197 pairs, with no differences in baseline characteristics after matching. In-house mortality, 30-day mortality and overall all-cause long-term mortality were comparable between the FT and the conventionally treated cohort. Postoperative anaesthetic care unit/intensive care unit length-of-stay (6.2 vs 20.6 h, P = 0.03) and postoperative ventilation times (158.9 vs 465.5 min, P < 0.001) were significantly shorter in the FT cohort. There were no differences in rates of postoperative adverse events. CONCLUSIONS: In centres with experienced anaesthesiologists, perioperative FT management is non-inferior to conventionally treated patients undergoing elective Bentall procedures without compromising patient safety. Abstract : Over the past 2 decades, fast-track (FT) concepts have been successfully implemented in cardiac surgery in up to 45% of cases, primarily in patients undergoing coronary artery bypass grafting (CABG), with no significant increases in morbidity and mortality [1–3].