Complete Metabolic Response in Adenocarcinoma Lung With Lymphangitic Carcinomatosis. (15th March 2023)

• Record Type: Journal Article
• Authors: Goyal, Harish; Kishore, Sai; Ganesan, Prasanth; Halanaik, Dhanapathi
• Is Part Of: Clinical nuclear medicine. Volume 48:Number 3(2023)
• Page Start: e133
• Page End: e134
• Publication Date: 2023-03-15
• Subjects: adenocarcinoma lung -- lymphangitic carcinomatosis -- 18F-FDG -- PET/CT -- complete metabolic response; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000004463
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract: Pulmonary lymphangitic carcinomatosis refers to the tumor spread into the lymphatic system of the lungs and is considered a poor prognostic marker. We present an interesting case of adenocarcinoma of right lung evaluated with 18 F-FDG PET/CT for baseline staging, with extensive bilateral lung involvement and lymphangitic carcinomatosis pattern. Subsequently, the patient received 3 cycles of carboplatin- and pemetrexed-based chemotherapy regimen along with oral ceritinib. Complete metabolic response and significant reduction in size of the primary lung lesion was noted on response evaluation with 18 F-FDG PET/CT, which is a rare phenomenon.