Left bundle branch blocks do not predict mortality in oldest-old patients hospitalized for COVID-19: The GERIA-COVID cohort study. (March 2023)

• Record Type: Journal Article
• Authors: Bannier, Adeline; Goldberg, Joëlle; Otekpo, Marie; Loison, Jocelyne; Gautier, Jennifer; Annweiler, Cédric
• Is Part Of: Maturitas. Volume 169(2023)
• Page Start: 32
• Page End: 34
• Publication Date: 2023-03
• Subjects: COVID-19 -- SARS-CoV-2 -- Intraventricular conduction disorders -- Bundle branch block -- Mortality -- Aged; COVID-19 Coronavirus disease 2019 -- SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 -- ACE2 Angiotensin-converting enzyme 2 -- ECG Electrocardiogram -- LBBB Left bundle branch block -- ICD Intraventricular conduction disturbances -- IQ Interquartile range -- HR Hazard ratio -- CI Confidence Interval -- GIR Iso Resource Groups; Climacteric -- Periodicals; Menopause -- Periodicals; Climacteric -- Periodicals; Geriatrics -- Periodicals; Menopause -- Periodicals; Middle Aged -- Periodicals; Climatère -- Périodiques; Ménopause -- Périodiques; Climacterium; Climacteric; Menopause; Electronic journals; Periodicals; 612.66
• DOI: 10.1016/j.maturitas.2023.01.002
• Languages: English
• ISSNs: 0378-5122

Abstract

Highlights: Cardiovascular comorbidities are recognized risk factors for COVID-19 severity. We found that left bundle branch blocks were not associated with 28-day and 3-month mortality in oldest-old patients hospitalized for COVID-19. Intraventricular conduction disorders are unlikely to explain COVID-19 severity in oldest-old adults. Abstract: This cohort study aimed to determine whether left bundle branch blocks (LBBB) in COVID-19 were associated with 28-day and 3-month mortality in oldest-old patients. LBBB were sought on electrocardiogram on hospital admission in patients aged 80 years or more admitted for COVID-19 to the geriatric acute care unit of Angers University Hospital, France, during the first wave of the pandemic. Eighty-five participants were included (mean ± SD, 88.3 ± 5.3 years; 48.2 % women; 14.1 % with LBBB; 18.8 % mortality after 28 days and 28.2 % after 3 months). LBBB was associated neither with 28-day (HR = 1.65, P = 0.58) nor with 3-month (HR = 1.08, P = 0.92) mortality, in fully-adjusted Cox regression.