Free‐running 3D whole‐heart T1 and T2 mapping and cine MRI using low‐rank reconstruction with non‐rigid cardiac motion correction. Issue 1 (5th October 2022)

• Record Type: Journal Article
• Authors: Phair, Andrew; Cruz, Gastão; Qi, Haikun; Botnar, René M.; Prieto, Claudia
• Is Part Of: Magnetic resonance in medicine. Volume 89:Issue 1(2023)
• Page Start: 217
• Page End: 232
• Publication Date: 2022-10-05
• Subjects: 3D radial -- cine imaging -- free‐running -- joint T1/T2$$ {T}_1/{T}_2 $$ mapping -- low‐rank inversion -- non‐rigid motion correction; Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.29449
• Languages: English
• ISSNs: 0740-3194

Abstract

Abstract : Purpose: To introduce non‐rigid cardiac motion correction into a novel free‐running framework for the simultaneous acquisition of 3D whole‐heart myocardial T 1 $$ {T}_1 $$ and T 2 $$ {T}_2 $$ maps and cine images, enabling a ∼ $$ \sim $$ 3‐min scan. Methods: Data were acquired using a free‐running 3D golden‐angle radial readout interleaved with inversion recovery and T 2 $$ {T}_2 $$ ‐preparation pulses. After correction for translational respiratory motion, non‐rigid cardiac‐motion‐corrected reconstruction with dictionary‐based low‐rank compression and patch‐based regularization enabled 3D whole‐heart T 1 $$ {T}_1 $$ and T 2 $$ {T}_2 $$ mapping at any given cardiac phase as well as whole‐heart cardiac cine imaging. The framework was validated and compared with established methods in 11 healthy subjects. Results: Good quality 3D T 1 $$ {T}_1 $$ and T 2 $$ {T}_2 $$ maps and cine images were reconstructed for all subjects. Septal T 1 $$ {T}_1 $$ values using the proposed approach ( 1200 ± 50 $$ 1200\pm 50 $$ ms) were higher than those from a 2D MOLLI sequence ( 1063 ± 33 $$ 1063\pm 33 $$ ms), which is known to underestimate T 1 $$ {T}_1 $$, while T 2 $$ {T}_2 $$ values from the proposed approach ( 51 ± 4 $$ 51\pm 4 $$ ms) were in good agreement with those from a 2D GraSE sequence ( 51 ± 2 $$ 51\pm 2 $$ ms). Conclusion: The proposed technique provides 3D T 1 $$ {T}_1 $$ and T 2 $$ {T}_2 $$ maps and cine images with isotropic spatial resolution in a single ∼ $$ \sim $$ 3.3‐min scan. Abstract : Click here for author‐reader discussions