Poly(acrylamide) Spheroids with Tunable Elasticity for Scalable Cell Culture Applications. Issue 1 (10th January 2023)

• Record Type: Journal Article
• Authors: Pieroth, Stephanie; Heras‐Bautista, Carlos O.; Hamad, Sarkawt; Brockmeier, Konrad; Hescheler, Jürgen; Pfannkuche, Kurt; Schmidt, Annette M.
• Other Names: Lederer Albena guestEditor.; Mutlu Hatice guestEditor.
• Is Part Of: Macromolecular chemistry and physics. Volume 224:Issue 1(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-01-10
• Subjects: Polymers -- Periodicals; Polymerization -- Periodicals; Synthetic products -- Periodicals; Macromolecules -- Periodicals; 547.7
• DOI: 10.1002/macp.202370005
• Languages: English
• ISSNs: 1022-1352

Abstract

Abstract : Microfluidics In article 2200246, Annette M. Schmidt's and her co‐workers' approach toward spherical, mm‐scaled PAAm hydrogel beads with adjustable, soft elastic properties as a matrix for scalable cell culture is described. The beads are produced by a continuous microfluidic approach, and after surface modification with biomarkers, their suitability as a matrix for scalable cell cultivation is successfully demonstrated with three different cell types in model experiments and in a tidal bioreactor system.