Upregulation of Superenhancer‐Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma (Adv. Sci. 1/2023). Issue 1 (4th January 2023)

Record Type:: Journal Article
Title:: Upregulation of Superenhancer‐Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma (Adv. Sci. 1/2023). Issue 1 (4th January 2023)
Main Title:: Upregulation of Superenhancer‐Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma (Adv. Sci. 1/2023)
Authors:: Peng, Jiang‐Yun
Cai, Dian‐Kui
Zeng, Ren‐Li
Zhang, Chao‐Yang
Li, Guan‐Cheng
Chen, Si‐Fan
Yuan, Xiao‐Qing
Peng, Li
Abstract:: Abstract : Mechanism of Superenhancer‐Driven LncRNA Accelerating Lipid Metabolism In article number 2204711, Li Peng and co‐workers reveal the mechanism of superenhancer‐related lncRNA functioning in lipid metabolism. It can be simulated by the accelerating vehicle. LncRNA FASRL is transcriptionally driven by USF1 via its superenhancer. FASRL binding to ACACA, a fatty acid synthesis rate‐limiting enzyme, increases lipid accumulation to exacerbate HCC.
Is Part Of:: Advanced science. Volume 10:Issue 1(2023)
Journal:: Advanced science
Issue:: Volume 10:Issue 1(2023)
Issue Display:: Volume 10, Issue 1 (2023)
Year:: 2023
Volume:: 10
Issue:: 1
Issue Sort Value:: 2023-0010-0001-0000
Page Start:: n/a
Page End:: n/a
Publication Date:: 2023-01-04
Subjects:: Science -- Periodicals
505
Journal URLs:: http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2198-3844 ↗
http://onlinelibrary.wiley.com/ ↗
DOI:: 10.1002/advs.202370004 ↗
Languages:: English
ISSNs:: 2198-3844
Deposit Type:: Legaldeposit
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