Development of DNA Biosensors Based on DNAzymes and Nucleases. (2nd January 2023)
- Record Type:
- Journal Article
- Title:
- Development of DNA Biosensors Based on DNAzymes and Nucleases. (2nd January 2023)
- Main Title:
- Development of DNA Biosensors Based on DNAzymes and Nucleases
- Authors:
- Yang, Hualin
Peng, Yu
Xu, Mingming
Xu, Shuxia
Zhou, Yu - Abstract:
- Abstract: DNA biosensors play important roles in environmental, medical, industrial and agricultural analysis. Many DNA biosensors have been designed based on the enzyme catalytic reaction. Because of the importance of enzymes in biosensors, we present a review on this topic. In this review, the enzymes were divided into DNAzymes and nucleases according to their chemical nature. Firstly, we introduced the DNAzymes with different function inducing cleavage, metalation, peroxidase, ligation and allosterism. In this section, the G-quadruplex DNAzyme, as a hot topic in recent years, was described in detail. Then, the nucleases-assisted signal amplification method was also reviewed in three categories including exonucleases, endonucleases and other nucleases according to the digestion sites in DNA substrates. In exonucleases section, the Exo I and Exo III were selected as examples. Then, the DNase I, BamH I, nicking endonuclease, S1 nuclease, the duplex specific nuclease (DSN) and RNases were chosen to illustrate the application of endonucleases. In other nucleases section, DNA polymerases and DNA ligases were detailed. Last, the challenges and future perspectives in the field were discussed.
- Is Part Of:
- Critical reviews in analytical chemistry. Volume 53:Number 1(2023)
- Journal:
- Critical reviews in analytical chemistry
- Issue:
- Volume 53:Number 1(2023)
- Issue Display:
- Volume 53, Issue 1 (2023)
- Year:
- 2023
- Volume:
- 53
- Issue:
- 1
- Issue Sort Value:
- 2023-0053-0001-0000
- Page Start:
- 161
- Page End:
- 176
- Publication Date:
- 2023-01-02
- Subjects:
- DNAzymes -- DNA biosensor -- enzyme catalytic reaction -- nucleases
Chemistry, Analytic -- Periodicals
543 - Journal URLs:
- http://www.tandfonline.com/toc/batc20/current ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/10408347.2021.1944046 ↗
- Languages:
- English
- ISSNs:
- 1040-8347
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3487.470000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 25669.xml