Caffeoyl esters from Aruncus sylvester and their improvement in movement disorder of MPTP-induced zebrafish embryos. (February 2023)

• Record Type: Journal Article
• Authors: Li, Jiaoyang; Peng, Rui; Zhu, Yi; Pang, Meijun; Su, Yanfang
• Is Part Of: Phytochemistry letters. Volume 53(2023)
• Page Start: 111
• Page End: 115
• Publication Date: 2023-02
• Subjects: Aruncus -- Caffeoyl -- Fructose -- Glucitol; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2022.12.005
• Languages: English
• ISSNs: 1874-3900

Abstract

Abstract: Two new caffeoyl esters, 5- O -( E )-caffeoyl- β -D -fructopyranose (1 ) and 6- O -( E )-caffeoyl-D -glucitol (2 ), together with a known compound, 3, 4-di- O -( E )-caffeoyl- β -D -glucopyranose (3 ), were isolated from the roots of Aruncus sylvester, and their structures were elucidated based on HRESIMS, 1D and 2D NMR, and IR spectroscopic data. Compounds 1 -3 improved the movement disorder of the MPTP-induced zebrafish embryos. Graphical Abstract: ga1 Highlights: Two new caffeoyl esters, 5- O -( E )-caffeoyl- β -D -fructopyranose and 6- O -( E )-caffeoyl-D -glucitol, were isolated from Aruncus sylvester . Their structures were elucidated by spectroscopic methods and hydrolysis. All compounds improved the movement disorder of the MPTP-induced zebrafish embryos. There were few reports on acylated β -D -fructopyranose.