Bacterial inactivation processes in water disinfection – mechanistic aspects of primary and secondary oxidants – A critical review. (1st March 2023)

• Record Type: Journal Article
• Authors: Jütte, Mischa; Abdighahroudi, Mohammad Sajjad; Waldminghaus, Torsten; Lackner, Susanne; V． Lutze, Holger
• Is Part Of: Water research. Volume 231(2023)
• Publication Date: 2023-03-01
• Subjects: Disinfection -- Secondary oxidants -- Ozone -- Chlorine dioxide -- Free available chlorine; ARB Antibiotic resistant bacteria -- ARG Antibiotic resistant gene -- bp Basepair -- BQ Benzoquinone -- ClO2 Chlorine dioxide -- DBPs Disinfection by-products -- DNA Deoxyribonucleic acid -- DOC Dissolved organic carbon -- FAB Free available bromine -- FAC Free available chlorine -- FAI Free available iodine -- GSH Glutathione -- HAA Haloacetic acids -- HAN Halogenated acetonitrile -- HGT Horizontal gene transfer -- HQ Hydroquinone -- Imin/max/ave Minimal / maximal / average inactivation -- MRG Multidrug resistant gene -- NDMA N-Nitrosodimethylamine -- NOM Natural organic matter -- O3 Ozone -- OH Hydroxylradical -- ROS Reactive oxygen species -- RNA Ribonucleic acid -- SQ Semiquinone -- SRFA Suwannee River fulvic acid -- SRNOM Suwannee River natural organic matter -- TEM Transmission electron microscopy -- THM Trihalomethanes -- WHO World health organization -- WWTPs Wastewater treatment plant; Water -- Pollution -- Research -- Periodicals; 363.7394
• DOI: 10.1016/j.watres.2023.119626
• Languages: English
• ISSNs: 0043-1354

Abstract

Highlights: Wild strains are more resistant towards oxidants compared to lab-cultivated strains. Ozone is the strongest broad band disinfectant. Chlorine dioxide is most effective for specific microorganisms. Secondary oxidants can be formed inside microbial cells. Secondary oxidants may contribute in inactivation of microbial cells. Abstract: Water disinfection during drinking water production is one of the most important processes to ensure safe drinking water, which is gaining even more importance due to the increasing impact of climate change. With specific reaction partners, chemical oxidants can form secondary oxidants, which can cause additional damage to bacteria. Cases in point are chlorine dioxide which forms free available chlorine (e.g., in the reaction with phenol) and ozone which can form hydroxyl radicals (e.g., during the reaction with natural organic matter). The present work reviews the complex interplay of all these reactive species which can occur in disinfection processes and their potential to affect disinfection processes. A quantitative overview of their disinfection strength based on inactivation kinetics and typical exposures is provided. By unifying the current data for different oxidants it was observable that cultivated wild strains (e.g., from wastewater treatment plants) are in general more resistant towards chemical oxidants compared to lab-cultivated strains from the same bacterium. Furthermore, it could be shown that for selective strains chlorine dioxide is the strongest disinfectant (highest maximum inactivation), however as a broadband disinfectant ozone showed the highest strength (highest average inactivation). Details in inactivation mechanisms regarding possible target structures and reaction mechanisms are provided. Thereby the formation of secondary oxidants and their role in inactivation of pathogens is decently discussed. Eventually, possible defense responses of bacteria and additional effects which can occur in vivo are discussed. Graphical abstract: Image, graphical abstract