Preparation of β-hydroxyketones (aldols) from the alkylation of O-silyl aryl cyanohydrins with epoxides. (17th February 2023)
- Record Type:
- Journal Article
- Title:
- Preparation of β-hydroxyketones (aldols) from the alkylation of O-silyl aryl cyanohydrins with epoxides. (17th February 2023)
- Main Title:
- Preparation of β-hydroxyketones (aldols) from the alkylation of O-silyl aryl cyanohydrins with epoxides
- Authors:
- Gilreath, Lissa D.
Melendez, Diamond R.
McGlade, Caylie A.
Shoemaker, Jennifer E.
Mullinax, Dakoda W.
Hartel, Aaron M. - Abstract:
- Graphical abstract: Abstract: β-Hydroxyketones (aldols) are prepared from the alkylation-deprotection of O -silylated aryl cyanohydrins with epoxides. Key to the success of the method was the suppression of an in situ cyclic imidate formation that occurs upon initial opening of the epoxide ring.
- Is Part Of:
- Tetrahedron letters. Volume 116(2023)
- Journal:
- Tetrahedron letters
- Issue:
- Volume 116(2023)
- Issue Display:
- Volume 116, Issue 2023 (2023)
- Year:
- 2023
- Volume:
- 116
- Issue:
- 2023
- Issue Sort Value:
- 2023-0116-2023-0000
- Page Start:
- Page End:
- Publication Date:
- 2023-02-17
- Subjects:
- Cyanohydrins -- Epoxides -- Aldols -- Imidates
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tetlet.2022.154334 ↗
- Languages:
- English
- ISSNs:
- 0040-4039
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.860000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 25671.xml