Mediastinal seminoma in the setting of advanced colorectal cancer: beware atypical sites of metastasis. Issue 2 (February 2023)

• Record Type: Journal Article
• Authors: Wakefield, Craig; Bird, Brian; Doddakula, Kishore; Burke, Louise
• Is Part Of: Diagnostic histopathology. Volume 29:Issue 2(2023)
• Page Start: 121
• Page End: 123
• Publication Date: 2023-02
• Subjects: extragonadal germ cell tumour -- immunohistochemistry -- mediastinal seminoma -- mediastinum -- thymus; Histology, Pathological -- Periodicals; Cytodiagnosis -- Periodicals; Diagnosis, Laboratory -- Periodicals; Pathology -- Periodicals; Histopathologie -- Périodiques; Pathologie -- Périodiques; Cytodiagnostics -- Périodiques; Diagnostics biologiques -- Périodiques; Histologie -- Technique -- Périodiques; Electronic journals; 616.07582
• DOI: 10.1016/j.mpdhp.2022.11.006
• Languages: English
• ISSNs: 1756-2317

Abstract

Abstract: Primary mediastinal seminoma is an uncommon malignant extragonadal germ cell tumour of the anterior mediastinum occurring almost exclusively in men. We report a case of mediastinal seminoma with prominent follicular lymphoid hyperplasia in a patient with metastatic colorectal cancer and discuss diagnostic considerations including prominent secondary change, immunohistochemical analysis and differential diagnosis.