Common atrioventricular valve surgery in children with functional single ventricle. (19th May 2021)

• Record Type: Journal Article
• Authors: Mayr, Benedikt; Burri, Melchior; Strbad, Martina; Cleuziou, Julie; Hager, Alfred; Ewert, Peter; Hörer, Jürgen; Lange, Rüdiger; Ono, Masamichi
• Is Part Of: European journal of cardio-thoracic surgery. Volume 60:Number 6(2021)
• Page Start: 1419
• Page End: 1427
• Publication Date: 2021-05-19
• Subjects: Single-ventricle physiology -- Common atrioventricular valve -- Valve repair; Heart -- Surgery -- Periodicals; Chest -- Surgery -- Periodicals; 617.54
• DOI: 10.1093/ejcts/ezab220
• Languages: English
• ISSNs: 1010-7940

Abstract

Abstract: : OBJECTIVES: A common atrioventricular valve (CAVV) is considered to be a risk factor for early and late deaths in patients with functional single ventricle (FSV). CAVV surgery in patients with FSV is challenging and there is limited knowledge of the outcomes of CAVV repair with univentricular physiology. METHODS: We reviewed all CAVV surgical procedures in patients with FSV who underwent univentricular palliation. End points of the study were survival after CAVV surgery and cumulative incidence of reoperation. RESULTS: Between 1984 and 2019, 66 children with CAVV and FSV underwent single-ventricle palliation, of whom 45.5% (30/66) required CAVV surgery. Indication for surgery was moderate CAVV regurgitation in 40% (12/30) and severe CAVV regurgitation in 60% (18/30). CAVV repair was performed in 93.3% (28/30) and CAVV replacement in 6.7% (2/30). The median age and weight at surgery were 0.9 years (interquartile range 0.3–1.8) and 6.5 kg (interquartile range 3.9–8.7), respectively. Operative and late mortality were 23.3% and 8.7%, respectively. Survival and cumulative incidence of reoperation at 4 years after CAVV surgery were 68.9% [standard deviation (SD): 8.7] and 35.8% (SD: 9.1), respectively. Fontan completion was achieved in 60% (18/30). Survival at 4 years after birth was 69.7% (SD: 8.5) in 30 patients with CAVV surgery, whereas it was 83% (SD: 6.3) in 36 patients without CAVV surgery ( P = 0.32). CONCLUSIONS: CAVV surgery in patients with FSV is associated with substantial mortality and a high incidence of reoperation. Abstract : Common atrioventricular valve (CAVV) is a single-orifice atrioventricular valve associated with complete atrioventricular septal defect (CAVSD) or univentricular heart (UVH) [1].