Recent developments in the treatment of renal cell carcinoma. (December 2013)

• Record Type: Journal Article
• Authors: Dutcher, Janice P.
• Is Part Of: Therapeutic advances in urology. Volume 5:Number 6(2013)
• Page Start: 338
• Page End: 353
• Publication Date: 2013-12
• Subjects: Renal cell carcinoma -- targeted therapy -- immunotherapy -- molecular subtypes; Urology -- Periodicals; Urologic Diseases -- therapy -- Periodicals; Genital Diseases, Male -- therapy -- Periodicals; Urologie -- Périodiques; 616.6005
• DOI: 10.1177/1756287213505672
• Languages: English
• ISSNs: 1756-2872

Abstract

Renal cell carcinoma (RCC) management has been imbued with new interest, in large part due to the recent success of new treatment options for advanced and metastatic disease. This has also been accompanied by less generally well known advances in the understanding of the molecular characterizations of subtypes of RCC with potential to lead to new therapeutic options. Additionally, the urologic oncology community is focusing on nephron-sparing surgical approaches with limited surgery if possible, and in conjunction with interventional radiologists, on ablative procedures for incidentally determined small renal masses. This report reviews some of the new biologic findings of adenocarcinoma of the kidney, and reviews the new therapeutics which continue to change the landscape for treatment of RCC.