Chemokines and Chemokine Receptors in Susceptibility to HIV-1 Infection and Progression to AIDS. Issue 3 (26th May 2013)

• Record Type: Journal Article
• Authors: Chatterjee, Animesh; Rathore, Anurag; Vidyant, Sanjukta; Kakkar, Kavita; Dhole, Tapan N.
• Is Part Of: Disease markers. Volume 32:Issue 3(2012)
• Page Start: 143
• Page End: 151
• Publication Date: 2013-05-26
• Subjects: HIV-1 infection -- Polymorphism -- Chemokine receptor -- Chemokines; Diagnosis -- Periodicals; Biochemical markers -- Periodicals; Pathology -- Periodicals; 616
• DOI: 10.3233/DMA-2011-0874
• Languages: English
• ISSNs: 0278-0240

Abstract

Abstract : A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor or co-receptor competitor and influences the susceptibility to HIV-1 infection and progression to AIDS in HIV-1 infected individuals.