Acute Hyperglycemia and In-Hospital Mortality in Spontaneous Intracerebral Hemorrhage. (6th January 2023)

• Record Type: Journal Article
• Authors: Gupta, Himanshu; Beshara, Simon; Katsanos, Aristeidis; Patil, Tushar; Al-Zahrani, Saeed; Chen, Jerry Yeou-Wei; Alharbi, Abdulrahman; Zamir, Nasim; Ng, Kelvin; Kase, Carlos S.; Shoamanesh, Ashkan
• Is Part Of: Canadian journal of neurological sciences. Volume 50:Number 1(2023)
• Page Start: 115
• Page End: 118
• Publication Date: 2023-01-06
• Subjects: Intracerebral hemorrhage -- Hyperglycemia -- Glucose -- Prognosis -- Mortality; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Electronic journals; 616.8
• DOI: 10.1017/cjn.2021.497
• Languages: English
• ISSNs: 0317-1671

Abstract

ABSTRACT: Hyperglycemia is reported to predict worse outcome in patients with stroke, including intracerebral hemorrhage (ICH). In 83 consecutive cases of ICH at a tertiary stroke center, hyperglycemia (serum glucose >7 mmol/L) compared to normoglycemia at presentation was associated with higher rates of in-hospital mortality (51.2% vs. 26.2%, OR 2.3, CI 1.2–7.6, p = 0.02). The association with in-hospital mortality withstood adjustment for age, ICH volume, intraventricular hemorrhage, and infratentorial ICH location, but not baseline Glasgow Coma Scale. Acute hyperglycemia is associated with in-hospital mortality in spontaneous ICH patients, though this may be an indirect, rather than a causal relationship.