Echocardiography indices in urbanized representatives of the Shor ethnic group with the presence of arterial hypertension. (14th October 2021) - Sumin, A
Abstract: : In patients with arterial hypertension, the detection of left ventricular hypertrophy has important clinical and prognostic significance. The use of published regulatory "control limits" remains limited and cannot be extended to other racial and ethnic groups. The aim of this study was to compare echocardiography indicators in patients with arterial hypertension from two ethnic groups living in the Gornaya Shoria region. Methods: The study included patients with arterial hypertension: 58 indigenous and 50 non-indigenous urbanized residents, comparable in age, and divided by ethnicity and gender into 4 groups: men of indigenous nationality (n=20), women of indigenous nationality (n=38), men of non-indigenous nationality (n=15) and women of non-indigenous nationality (n=35). All of them underwent echocardiographic examination. Results: The body weight and BSA were lower in men and women of Shor ethnicity than in men and women of non-indigenous ethnicity (p=0.0014 and p=0.004). LAi was significantly larger in men of Shor nationality (p=0.049), at the same time, the size of their RA was the smallest (p=0.04). The data of the longitudinal LV systolic function in the form of a systolic excursion of the septum (s'sept) were the highest in Shor men (p=0.004), and the LV performance index was the lowest in them (p=0.012). Also in this group, the minimum isovolumic relaxation time (p=0.03) and the highest rate of early diastolic filling of the LV (p=0.04) were noted. When assessing correlations independent factors associated with pronounced LVH were glucose, DBP, and urea in Shor patients. Non-indigenous nationality independent factors associated with pronounced LVH were waist circumference and DBP. Conclusion: Echocardiographic examination of patients with hypertension revealed the features of structural and functional indicators in the representatives of the indigenous urbanized population of the Mountain Shoria in comparison with the representatives of the non-indigenous population. This study can be useful in assessing the impact of the development of arterial hypertension, as well as the impact of changing the lifestyle of the Shors when moving to the city from rural areas on ethnic differences in echocardiography. Funding Acknowledgement: Type of funding sources: None.