Synthesis of MoS2 nanosheets drug delivery system and its drug release behaviors. Issue 1 (20th July 2021)

• Record Type: Journal Article
• Authors: Wang, Feng; Lv, Fang-Yuan; Liu, Kui-Long; Li, Zhi-Hao; Niu, Shu; Zhang, Yun-Yi; Cong, Hai-Lin; Shen, You-Qing; Yu, Bing
• Is Part Of: Ferroelectrics. Volume 578:Issue 1(2021)
• Page Start: 31
• Page End: 39
• Publication Date: 2021-07-20
• Subjects: MoS2 nanosheets -- photothermal conversion -- esterase-responsive -- drug release; Ferroelectricity -- Periodicals; Ferroelectric crystals -- Periodicals; 537
• DOI: 10.1080/00150193.2021.1902761
• Languages: English
• ISSNs: 0015-0193

Abstract

Abstract: A MoS2 nanosheets drug delivery system with photothermal conversion ability was synthesized. The drug loading content of the synthesized was as high as 24.5%. The drug HCPT was modified by lipoic acid (LA) and connected onto MoS2 nanosheets through S-Mo bond, which is more stable than physical adsorption. Due to the ester bond between HCPT and MoS2 nanosheets, the drug delivery system could responsively release HCPT when exposed to esterase.