PH-responsive dendrimer-functionalized cotton cellulose nanocrystals for effective cancer treatment. Issue 1 (20th July 2021)

• Record Type: Journal Article
• Authors: Zou, Wen-Tao; Zhong, Wei; Sun, Meng-Ge; Li, Yao; Pang, Long; Cong, Hai-Lin; Shen, You-Qing; Yu, Bing
• Is Part Of: Ferroelectrics. Volume 578:Issue 1(2021)
• Page Start: 108
• Page End: 112
• Publication Date: 2021-07-20
• Subjects: Dendrimer -- drug delivery -- cellulose; Ferroelectricity -- Periodicals; Ferroelectric crystals -- Periodicals; 537
• DOI: 10.1080/00150193.2021.1902769
• Languages: English
• ISSNs: 0015-0193

Abstract

Abstract: Natural organic nanoparticle cellulose nanocrystals (CNCs) with good biocompatibility and unique physical and chemical properties have been proved to be promising materials for drug delivery systems. In this study, a CNC with rich. It has the property of modifying dendrimers. The polymer has good biocompatibility and stability. TEM shows that CNC has a good particle size, about 154–200 nm. And after modifying the amine group, the polymer still has good dispersibility. Because CNC-NH2 has a good size, it can better bypass the human body clearance system and enter cancer cells.