TGF-β Signaling in Neuronal Stem Cells. Issue 4 (2008)

• Record Type: Journal Article
• Authors: Yun, Chohee; Mendelson, Jonathan; Blake, Tiffany; Mishra, Lopa; Mishra, Bibhuti
• Is Part Of: Disease markers. Volume 24:Issue 4/5(2008)
• Page Start: 251
• Page End: 255
• Publication Date: 2008
• Subjects: Diagnosis -- Periodicals; Biochemical markers -- Periodicals; Pathology -- Periodicals; 616
• DOI: 10.1155/2008/747343
• Languages: English
• ISSNs: 0278-0240

Abstract

Abstract : Transforming growth factor beta (TGF- β ) signaling has diverse and complex roles in various biological phenomena such as cell growth, differentiation, embryogenesis and morphogenesis. ES cells provide an essential model for understanding the role of TGF- β signaling in lineage specification and differentiation. Recent studies have suggested significant role of TGF- β in stem/progenitor cell biology. Here in this review, we focus on the role of the TGF- β superfamily in neuronal development.