Long‐term results of artificial urinary sphincter implantation for urinary incontinence due to intrinsic sphincter deficiency in children. Issue 1 (26th November 2022)

• Record Type: Journal Article
• Authors: Paret, Fanny; Leclair, Marc‐David; Karam, Georges; Rigaud, Jérôme; Baron, Maximilien; Perrouin‐Verbe, Marie‐Aimée
• Is Part Of: Neurourology and urodynamics. Volume 42:Issue 1(2023)
• Page Start: 355
• Page End: 365
• Publication Date: 2022-11-26
• Subjects: artificial urinary sphincter -- children -- intrinsic sphincter deficiency -- neurogenic bladder -- urinary incontinence; Urinary organs -- Periodicals; Urodynamics -- Periodicals; Urology -- Periodicals; 616.6
• DOI: 10.1002/nau.25106
• Languages: English
• ISSNs: 0733-2467

Abstract

Abstract: Purpose: To report long‐term results of artificial urinary sphincter implantation for urinary incontinence due to intrinsic sphincter deficiency in children. Materials and Methods: This retrospective monocentric study included all patients who underwent artificial urinary sphincter (AMS 800) implantation before 18 years of age between 1986 and October 2018 for intrinsic sphincter deficiency. The primary outcome was the continence rate at the last follow‐up, defined by the daily use of 0 pads. The secondary outcome was the overall survival of the device, defined as the absence of any repeated surgery (revision or explantation) during follow‐up. Reoperation‐free, revision‐free, and explantation‐free device survival rates were estimated using the Kaplan–Meier method. Results: Thirty‐six patients with a median age of 12 years (interquartile range [IQR]: 10–14) were included (15 females, 21 males). The median follow‐up was 18.7 years (IQR: 9–26). The main underlying condition was spinal dysraphism ( n = 24; 67%). The median time to the first reoperation was 9 years (IQR: 3.75–14.7). At the last follow‐up, survival rates without revision were 84%, 71%, 55%, and 33% at 5, 10, 15, and 20 years, respectively. Survival rates without explantation were 91%, 84%, 80%, and 72% at 5, 10, 15, and 20 years, respectively. At the last follow‐up, 29 patients had a functional device. The overall continence rate was 88%. All patients who had their device still in place were continent at the last follow‐up. Conclusion: The artificial urinary sphincter is an effective long‐term treatment for urinary incontinence related to intrinsic sphincter deficiency in children, providing a high rate of continence, even if associated with a high rate of reoperation.