Near-Infrared Fluorescence Optical Imaging and Tomography. Issue 2 (12th June 2013)
- Record Type:
- Journal Article
- Title:
- Near-Infrared Fluorescence Optical Imaging and Tomography. Issue 2 (12th June 2013)
- Main Title:
- Near-Infrared Fluorescence Optical Imaging and Tomography
- Authors:
- Gurfinkel, Michael
Ke, Shi
Wen, Xiaoxia
Li, Chun
Sevick-Muraca, Eva M. - Abstract:
- Abstract : The advent of recent advances in near-infrared laser diodes and fast electro-optic detection has spawned a new research field of diagnostic spectroscopy and imaging based on targeting and reporting exogenous fluorescent agents. This review seeks to concisely address the physics, instrumentation, advancements in tomography, and near-infrared fluorescent contrast agent development that promises selective and specific molecular targeting of diseased tissues. As an example of one area of the field, recent work focusing on pharmacokinetic analysis of fluorophores targeting the epidermal growth factor receptor (EGFR) is presented in a human breast cancer xenograft mouse model to demonstrate specificity of molecularly targeted contrast agents. Finally, a critical evaluation of the limitations and the opportunities for future translation of fluorescence-enhanced optical imaging of deep tissues is presented.
- Is Part Of:
- Disease markers. Volume 19:Issue 2/3(2003)
- Journal:
- Disease markers
- Issue:
- Volume 19:Issue 2/3(2003)
- Issue Display:
- Volume 19, Issue 2/3 (2003)
- Year:
- 2003
- Volume:
- 19
- Issue:
- 2/3
- Issue Sort Value:
- 2003-0019-NaN-0000
- Page Start:
- 107
- Page End:
- 121
- Publication Date:
- 2013-06-12
- Subjects:
- Diagnosis -- Periodicals
Biochemical markers -- Periodicals
Pathology -- Periodicals
616 - Journal URLs:
- https://www.hindawi.com/journals/dm/ ↗
- DOI:
- 10.1155/2004/474818 ↗
- Languages:
- English
- ISSNs:
- 0278-0240
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 25594.xml