Changes in prescription patterns and doses of oral antidiabetic drugs in Japanese patients with type 2 diabetes (JDDM70). Issue 1 (21st October 2022)

• Record Type: Journal Article
• Authors: Shirabe, Shinichiro; Yamazaki, Katsuya; Oishi, Mariko; Arai, Keiko; Yagi, Noriharu; Sato, Manaka; Takeuchi, Masakazu; Kai, Takahito; Maegawa, Hiroshi
• Is Part Of: Journal of diabetes investigation. Volume 14:Issue 1(2023)
• Page Start: 75
• Page End: 80
• Publication Date: 2022-10-21
• Subjects: Diabetes mellitus, type 2 -- Hypoglycemic agents -- Japan; Diabetes -- Periodicals; Diabetes -- Research -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462005
• DOI: 10.1111/jdi.13922
• Languages: English
• ISSNs: 2040-1116

Abstract

ABSTRACT: We assessed the prescription patterns of oral antidiabetic drugs in Japanese patients with type 2 diabetes between 2002 and 2020 using data from the Computerized Diabetes Care database. Among 172, 960 patients treated with oral antidiabetic drugs, both the sulfonylurea prescription rate and dose decreased from 2002 to 2020. Prescriptions of biguanides, dipeptidyl peptidase‐4 inhibitors and sodium–glucose cotransporter 2 inhibitors increased; their dose and dose frequency remained relatively stable. Trends in oral antidiabetic drug prescriptions changed over time, reflecting guideline recommendations and existing evidence. Abstract : This study using a large diabetes database in Japan assessed prescription patterns of oral antidiabetic drugs in patients with type 2 diabetes and reported a steady decrease in sulfonylurea prescriptions and dose from 2002 to 2020. Conversely, prescriptions for biguanides, dipeptidyl peptidase‐4 inhibitors, and sodium‐glucose cotransporter 2 inhibitors increased, with their doses and dose frequencies remaining relatively stable over time.