PAIN-RELATED BRAIN STRUCTURE AND PAIN CATASTROPHIZING IN BLACKS AND WHITES WITH KNEE OSTEOARTHRITIS. (8th November 2019)

• Record Type: Journal Article
• Authors: Terry, Ellen; Terry, Ellen L; Cardoso, Josue S; Sibille, Kimberly T; Tanner, Jared J; Goodin, Burel R; Price, Catherine C; Fillingim, Roger B
• Is Part Of: Innovation in aging. Volume 3(2019)Supplement 1
• Page Start: S71
• Page End: S71
• Publication Date: 2019-11-08
• Subjects: Aging -- Periodicals; Gerontology -- Periodicals; 612.67
• DOI: 10.1093/geroni/igz038.276
• Languages: English
• ISSNs: 2399-5300

Abstract

Abstract: Pain catastrophizing is a cognitive-affective response during painful experiences and is implicated in the facilitation of pain processing. Non-Hispanic blacks (NHB) more often engage in catastrophizing as a coping strategy compared to non-Hispanic whites (NHW). Hence, pain catastrophizing may contribute to poorer pain-related outcomes and greater disability in NHBs. Functional neuroimaging studies have linked high levels of catastrophizing with increased cerebral responses to pain in the insula and primary somatosensory cortex [S1], but associations between brain structure and catastrophizing remain largely unexplored. Moreover, no neuroimaging studies have investigated whether catastrophizing is differentially associated with pain-related brain structure across racial/ethnic groups. We examined the association between race/ethnicity, catastrophizing, and pain-related brain structure (insula, S1) among 176 participants with and without knee pain. Findings provide evidence for differing associations of catastrophizing with pain-related brain structures in NHBs and NHWs. It is therefore important to develop culturally-relevant, neural-mediated interventions targeting catastrophizing for NHBs.