Bioaccessibility of polycyclic aromatic hydrocarbons in central air conditioner filter dust and its occupational exposure to shopping mall employees. (March 2019)

• Record Type: Journal Article
• Authors: Liu, Yan; Wang, Suhan; Hu, Jian; Wu, Bing; Huang, Cunrui; He, Chuan; Zheng, Zelin; Gao, Peng
• Is Part Of: Environmental pollution. Volume 246(2019)
• Page Start: 896
• Page End: 903
• Publication Date: 2019-03
• Subjects: Polycyclic aromatic hydrocarbons -- Air conditioner filter -- Build environment -- Occupational exposure -- Ingestion -- Inhalation; Pollution -- Periodicals; Pollution -- Environmental aspects -- Periodicals; Environmental Pollution -- Periodicals; Pollution -- Périodiques; Pollution -- Aspect de l'environnement -- Périodiques; Pollution -- Effets physiologiques -- Périodiques; Pollution; Pollution -- Environmental aspects; Periodicals; Electronic journals; 363.73
• DOI: 10.1016/j.envpol.2018.12.093
• Languages: English
• ISSNs: 0269-7491

Abstract

Abstract: The assessment of the human health risk of dust exposure to polycyclic aromatic hydrocarbons (PAHs) has been hampered by a lack of data on the bioaccessibility. The purpose of this study was to apply in vitro methods using simulated lungs with artificial lysosomal fluid (ALF) and Gamble's solution and digestive fluid to assess the bioaccessibility of 8 high molecular weight PAH (PAH8 ) in central air conditioner (AC) filter dust from a shopping mall in northeast China. Overall, the bioaccessible PAH8 concentration (μg/g) in AC filter dust samples after ALF and Gamble's solution extraction for 24 h were notable, with a mean of 1.71 ± 0.6 and 1.92 ± 0.5 in the sales areas, and a mean of 1.61 ± 0.2 and 1.85 ± 0.2 in the office areas. AC filter dust exposed to simulated digestive fluid had a mean bioaccessible PAH8 concentration (μg/g) of 1.60 ± 0.4 in the sales areas and 1.15 ± 0.2 in the office areas. Benzo[b]fluoranthene (BbF) made the most significant contribution to the total and bioaccessible PAH8 concentrations in all of the AC filter dust after simulated digestive fluid extraction, while the bioaccessibility was driven by chrysene (Chr, sales areas) and indeno[1, 2, 3-c, d]pyrene (Ind, office areas). Both the bioaccessibility and concentration of PAH8 in simulated lung fluid were mainly driven by benzo[a]pyrene (BaP). This study highlights the need to conduct bioaccessibility experiments for an adequate exposure assessment of health risk. Graphical abstract: Image 1 Highlights: Bioaccessibility of PAH8 in air conditioner (AC) filter dust was assessed. The spatial distribution and composition of bioaccessible PAH8 in simulated biological fluids were examined. Occupational exposure posed by AC filter dust was calculated using PAH8 inhalation and ingestion bioaccessibility. Abstract : Bioaccessibility assessment of PAHs via indoor suspension dust.