Intraoperative Indocyanine Green Fluorescence Angiography Is Sensitive for Predicting Postoperative Wound Complications in Soft-Tissue Sarcoma Surgery. Issue 10 (15th May 2021)

• Record Type: Journal Article
• Authors: Wilke, Benjamin K.; Schultz, Douglas S.; Huayllani, Maria T.; Boczar, Daniel; Spaulding, Aaron C.; Sherman, Courtney E.; Murray, Peter M.; Forte, Antonio J.
• Is Part Of: Journal of the American Academy of Orthopaedic Surgeons. Volume 29:Issue 10(2021)
• Publication Date: 2021-05-15
• Subjects: Orthopedics -- Periodicals; Orthopedic surgery -- Periodicals; Joint Diseases -- Periodicals; Orthopedics -- Periodicals; Orthopedic surgery; Orthopedics; Periodicals; 616.7005
• DOI: 10.5435/JAAOS-D-20-00355
• Languages: English
• ISSNs: 1067-151X

Abstract

Abstract : Introduction: Indocyanine green (ICG) angiography is a novel technology that has been predictive of postoperative wound complications. It is unknown whether this technology can successfully predict complications after sarcoma resection. In this study, we aimed to evaluate the sensitivity and specificity of ICG angiography in predicting postoperative wound complications after soft-tissue sarcoma resection. Methods: A prospective cohort study of 23 patients was performed beginning October 2017 at our institution. Patients who underwent soft-tissue sarcoma resection were included. After tumor resection and wound closure, evaluation of tissue perfusion in skin edges was performed with ICG angiography. Wound complications were recorded in the postoperative follow-up. Results: Eight patients developed postoperative wound complications. Six patients were predicted to have wound complications on the final ICG scans. The accuracy of ICG angiography was dependent on the anatomic location, with improved accuracy in the lower extremity. ICG angiography had a sensitivity of 50%, a specificity and a positive predictive value of 100%, and a negative predictive value of 70% for wound complications after soft-tissue sarcoma resections located in the lower extremity. Conclusion: ICG angiography has a high predictive value in the lower extremity for postoperative wound complications. Level of Evidence: Level III, Diagnostic