Association of Childhood Atopic Dermatitis With Atopic and Nonatopic Multimorbidity. Issue 4 (July 2021)

• Record Type: Journal Article
• Authors: Cheng, Brian T.; Silverberg, Nanette B.; Silverberg, Jonathan I.
• Is Part Of: Dermatitis. Volume 32:Issue 4(2021)
• Publication Date: 2021-07
• Subjects: Skin -- Inflammation -- Periodicals; Skin -- Diseases -- Periodicals; Dermatology -- Periodicals; Dermatitis, Contact -- Periodicals; Dermatitis, Atopic -- Periodicals; Dermatitis, Occupational -- Periodicals; Drug Eruptions -- Periodicals; 616.51
• DOI: 10.1097/DER.0000000000000644
• Languages: English
• ISSNs: 1710-3568

Abstract

Abstract : Background: Little is known about the impact of multimorbidity in childhood atopic dermatitis (AD). Objective: We sought to determine the likelihood and predictors of chronic disease multimorbidity in childhood AD. Methods: Data were examined for children (<18 years) in the 1996–2015 Medical Expenditure Panel Survey, an annual, representative sample of United States households. Multimorbidity was assessed using Charlson Comorbidity Index (CCI), Healthcare Utilization Project Chronic Comorbidity Indicator (HCUP-CCI) and frequency of atopic comorbidities. Results: Young children with mild-moderate and severe AD, and adolescents with mild-moderate AD had higher CCI scores. Similarly, young children and adolescents with mild-moderate and severe AD had increased HCUP-CCI scores. Children with AD and atopic disease had higher CCI and HCUP-CCI scores than children with either alone. Young children and adolescents with mild-moderate and severe AD had more atopic comorbidities. Conclusions: Pediatric AD is associated with increased atopic and non-atopic multimorbidity. Comorbid atopic disease may identify a subset of children with AD who particularly benefit from enhanced screening and management of multimorbidity. Abstract : Supplemental digital content is available in the text.