A case of valproate-induced hyperammonaemic encephalopathy. Issue 1 (February 2013) - Lucie, O
We report the case of a 65-year-old woman with hyperammonaemic encephalopathy induced by sodium valproate. This is a rare complication of treatment with sodium valproate. The encephalopathy can be reversible on withdrawal of treatment and does carry a risk of morbidity and mortality. This case demonstrates the importance of recognising this potential complication of a drug in common use.