Squamous Cell Carcinoma Mimicking Neck Paraganglioma on 68Ga-DOTATATE PET/CT. (July 2021)

• Record Type: Journal Article
• Authors: Civan, Caner; Isik, Emine Goknur; Has Simsek, Duygu; Sen, Comert; Unal, Seher Nilgun
• Is Part Of: Clinical nuclear medicine. Volume 46:Number 7(2021)
• Publication Date: 2021-07
• Subjects: squamous cell carcinoma -- larynx -- 68Ga-DOTATATE -- PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003555
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Somatostatin receptor (SSTR) imaging with 68 Ga-labeled somatostatin analogs has been used for many tumors with high SSTR expression. Increased uptake mostly depends on the SSTR status of tumors; however, false-positive uptake can be demonstrated in benign diseases or other malignancies because of the increased SSTR expression. We present a case of a 50-year-old man with increased SSTR activity on cervical lesion located in internal jugular chain in 68 Ga-DOTATATE PET/CT, which was performed for suspicion of paraganglioma. Biopsy revealed lymph node metastasis of squamous cell carcinoma other than paraganglioma. 18 F-FDG PET/CT showed primary malignancy on larynx and lymph node metastasis, which were correlated surgically.