Concurrent Subcutaneous Panniculitis-like T-Cell Lymphoma and B-Cell Acute Lymphoblastic Leukemia in 2 Pediatric Patients. Issue 6 (August 2021)

• Record Type: Journal Article
• Authors: Smith, Geoffrey A.; Levinson, Anya L.; Galvin, Robert T.; Lalor, Leah E.; McCalmont, Timothy; Wang, Linlin; Geis, Michael C.; Odegaard, Karah; Hupp, Meghan; Maguiness, Sheilagh; Turcotte, Lucie M.; Cordoro, Kelly M.; Hermiston, Michelle L.
• Is Part Of: Journal of pediatric hematology/oncology. Volume 43:Issue 6(2021)
• Publication Date: 2021-08
• Subjects: ALL -- SPTCL -- concurrent malignancy -- immune dysregulation -- clinical decision making; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000001921
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Subcutaneous panniculitis-like T-cell lymphoma is a cutaneous lymphoma characterized by CD8 + T-cell infiltrate in the subcutis that is rare in children. Acute lymphoblastic lymphoma is the most common pediatric malignancy and often presents with fevers and pancytopenia. Herein, we report 2 pediatric patients presenting with subcutaneous panniculitis-like T-cell lymphoma and B-cell acute lymphoblastic lymphoma, distinct hematologic malignancies arising from different lymphoid lineages, with no identifiable germline cancer predisposition.