Diffusion of Pneumocystis jirovecii in the surrounding air of patients with Pneumocystis colonization: frequency and putative risk factors. (2nd November 2016)

• Record Type: Journal Article
• Authors: Fréalle, Emilie; Valade, Sandrine; Guigue, Nicolas; Hamane, Samia; Chabé, Magali; Le Gal, Solène; Damiani, Céline; Totet, Anne; Aliouat, El Moukhtar; Nevez, Gilles; Menotti, Jean
• Is Part Of: Medical mycology. Volume 55:Number 5(2017)
• Page Start: 568
• Page End: 572
• Publication Date: 2016-11-02
• Subjects: Pneumocystis jirovecii -- Pneumocystis colonization -- air shedding -- real-time PCR -- mtLSU genotype; Medical mycology -- Periodicals; Veterinary mycology -- Periodicals; Mycology -- Periodicals; Mycoses -- Periodicals; Pathogenic fungi -- Periodicals; 616.969005
• DOI: 10.1093/mmy/myw113
• Languages: English
• ISSNs: 1369-3786

Abstract

Abstract: In a prospective bicentric study, Pneumocystis jirovecii excretion and diffusion was explored in air samples collected in the rooms occupied by 17 Pneumocystis -colonized patients. P. jirovecii DNA was detected by real-time PCR in the air collected from 3 patients' rooms (17.6%), with identical genotypes in corresponding clinical and air samples. Pneumocystis DNA was detected for 2/3 patients with autoimmune disease treated with corticosteroids versus 1/6 patients with hematologic disease and 0/5 kidney transplant recipients. These data confirm the possible excretion of the fungus by Pneumocystis -colonized patients and thus bring additional arguments for the prevention of airborne transmission in hospital wards.