Trends in the incidence of ovarian cancer in sub‐Saharan Africa. Issue 7 (7th November 2022)

• Record Type: Journal Article
• Authors: Gizaw, Muluken; Parkin, Donald Maxwell; Stöter, Ole; Korir, Anne; Kamate, Bakarou; Liu, Biying; Bojang, Lamin; N'Da, Guy; Manraj, Shyam S.; Bukirwa, Phiona; Chokunonga, Eric; Chingonzoh, Tatenda; Peko, Jean‐Félix; Finesse, Anne; Somdyala, Nontuthuzelo; Ladipo, Akinade; Kantelhardt, Eva Johanna
• Is Part Of: International journal of cancer. Volume 152:Issue 7(2023)
• Page Start: 1328
• Page End: 1336
• Publication Date: 2022-11-07
• Subjects: epithelial -- incidence -- ovarian cancer -- sub‐Saharan Africa -- trends; Cancer -- Periodicals; Cancer -- Prevention -- Periodicals; 616.994
• DOI: 10.1002/ijc.34335
• Languages: English
• ISSNs: 0020-7136

Abstract

Abstract: Ovarian cancer (OC) is one of the commonest cancers of women in sub‐Saharan Africa (SSA), although to date no data have been available on time trends in incidence to better understand the disease pattern in the region. We estimate time trends by histological subtype from 12 population‐based cancer registries in 11 countries: Kenya (Nairobi), Mauritius, Seychelles, Uganda (Kampala), Congo (Brazzaville), Zimbabwe (Bulawayo and Harare), Cote d'Ivoire (Abidjan), The Gambia, Mali (Bamako), Nigeria (Ibadan) and South Africa (Eastern Cape). The selected registries were those that could provide consistent estimates of the incidence of ovarian cancer and with quality assessment for periods of 10 or more years. A total of 5423 cases of OC were included. Incidence rates have been increasing in all registries except Brazzaville, Congo, where a nonsignificant decline of 1% per year was seen. Statistically significant average annual increases were seen in Mauritius (2.5%), Bamako (5.3%), Ibadan (3.9%) and Eastern Cape (8%). Epithelial ovarian cancer was responsible for the increases observed in all registries. Statistically significant average annual percentage changes (AAPC) for epithelial OC were present in Bamako (AAPC = 5.9%), Ibadan (AAPC = 4.7%) and Eastern Cape (AAPC = 11.0%). Creating awareness among professionals of the growing importance of the disease is surely an important step to improving availability of, and access to, diagnosis and treatment of OC in SSA. Support must be given to the cancer registries to improve the availability of good‐quality data on this important cancer. Abstract : What's new? Ovarian cancer is one of the most common cancers in sub‐Saharan Africa. Here, the authors investigate changes in ovarian cancer incidence over time. They analysed data from 12 population‐based cancer registries representing multiple regions, for a total of 5423 cases of ovarian cancer over a period of at least 10 years. Incidence rates, they found, have increased in all regions except Brazzaville, Congo. These trends point to the need for improving ovarian cancer care in Africa, as well as improvements to cancer registries to expand the areas where strong epidemiological data is being collected.