A Two-in-One Tumor in the Adrenal: A Functional Adrenocortical Adenoma with Myelolipomatous Differentiation. (2nd January 2023)

• Record Type: Journal Article
• Authors: Bhardwaj, Sunny; Deshpande, Rohit Sanjay; Kumar, Santosh; Mitra, Suvradeep
• Is Part Of: Fetal and pediatric pathology. Volume 42:Number 1(2023)
• Page Start: 161
• Page End: 166
• Publication Date: 2023-01-02
• Subjects: Adrenocortical adenoma -- myelolipoma -- pediatric -- myelolipomatous differentiation -- Cushing syndrome; Pathology, Molecular -- Periodicals; Pediatrics -- Periodicals; Molecular biology -- Periodicals; Pediatric pathology -- Periodicals; Fetal Diseases -- pathology -- Periodicals; Infant, Newborn, Diseases -- pathology -- Periodicals; Pediatrics -- Periodicals; 618.92007
• DOI: 10.1080/15513815.2022.2072423
• Languages: English
• ISSNs: 1551-3815

Abstract

Abstract: Background: Adrenocortical adenoma (ADA) and myelolipoma are two common benign neoplasms of the adrenal cortex that have been reported to occur together. Case report: A 14-year-old girl presented with the features of ACTH-independent endogenous Cushing syndrome. Abdominal CECT revealed a left adrenal 2.3 × 1.8 × 1.5 cm arterially enhancing nodular lesion with central hypodensity. Histologically, this was an ADA with oncocytic change and myelolipomatous differentiation/metaplasia. Discussion/Conclusion: ADA with myelolipomatous differentiation/metaplasia can occur in the pediatric age group.