Simulation of physical activities effect and treatment exogenous insulin for managing plasma glucose concentration in type 1 diabetes mellitus. (June 2020)

• Record Type: Journal Article
• Authors: Kartono, A; Sari, M; Wahyudi, S T
• Is Part Of: Journal of physics. Volume 1572(2020)
• Publication Date: 2020-06
• Subjects: Physics -- Congresses; 530.5
• DOI: 10.1088/1742-6596/1572/1/012060
• Languages: English
• ISSNs: 1742-6588

Abstract

Abstract: The simulation model of glucose level dynamics system during physical activity is important to represent an actually of the normal living conditions. These simulation results can be to accelerate the development of the artificial pancreatic design because of an administration of glucose through the oral according to the actual conditions then followed by administering insulin through infusion is following the actual conditions. In this study, the effects of insulin injection and physical activity on the glucose concentration level of type 1 diabetes mellitus (T1DM) will be simulated. A modified oral minimal model using the effects of physical activity and external insulin treatment was developed in the present study. Based on this simulation study, the main objective of this study was to vary insulin injections while carrying out physical activities that could validate the effects of decreased blood glucose levels in T1DM patients. These simulation results showed that the greater the injection of insulin during physical activity, the faster the rate of blood glucose concentration decreases. The optimum experiment simulation has been obtained to represent a treatment accurately by comparing the experimental data of a normal glucose concentration.