Occurrence and clinical course of peri-stent contrast staining: comparison between second-generation drug-eluting stents and third generation drug-eluting stents. (25th November 2020)

• Record Type: Journal Article
• Authors: Mori, S; Ito, Y; Kishida, T; Fukagawa, T; Nakano, T; Makino, K; Mizusawa, M; Shirai, S; Honda, Y; Tsutsumi, M; Sakamoto, Y; Kobayashi, N; Araki, M; Yamawaki, M; Hirano, K
• Is Part Of: European heart journal. Volume 41:(2020)Supplement 2
• Publication Date: 2020-11-25
• Subjects: Coronary Artery Disease - Epidemiology, Prognosis, Outcome; Cardiology -- Periodicals; Heart -- Diseases -- Periodicals; 616.12005
• DOI: 10.1093/ehjci/ehaa946.1322
• Languages: English
• ISSNs: 0195-668X

Abstract

Abstract: Background: Peri-stent contrast staining (PSS) has been reported to be associated with very late stent thrombosis. The aims of this study was to compare the occurrence rate of PSS between second generation drug-eluting stents (2nd DES) and third generation drug-eluting stents (3rd DES), and to identify clinical characteristics associated with PSS. Methods and results: This study comprised 1899 patients with 2493 de novo lesions treated with 2nd or 3rd DES from October 2015 to September 2018. Follow-up angiography was available for 1883 lesions (75.5%). There were 725 patients with 968 lesions treated with 2nd DES, and 716 patients with 915 lesions treated with 3rd DES. The occurrence of PSS, types of PSS, and VLST related to PSS were compared between 2nd and 3rd DES implantation. Mean follow-up period was 30±12 months. The occurrence rate of PSS and segmental type of PSS were similar between two groups (2nd DES vs. 3rd DES, 1.5% vs. 1.7%, p=0.73, 47% vs. 50%, p=0.85, and respectively). The VLST related to PSS occurred in only one case in 3rd DES group. (0% vs. 6.3%, p=0.33). Conclusion: The occurrence rate of PSS and clinical course were similar between 2nd and 3rd DES. Funding Acknowledgement: Type of funding source: None