Standardization of assay representation in the Ontology for Biomedical Investigations. (9th July 2021)

• Record Type: Journal Article
• Authors: Vita, Randi; Zheng, Jie; Jackson, Rebecca; Dooley, Damion; Overton, James A; Miller, Mark A; Berrios, Daniel C; Scheuermann, Richard H; He, Yongqun; McGinty, Hande Küçük; Brochhausen, Mathias; Lin, Aisyah Yu; Jain, Sagar B; Chibucos, Marcus C; Judkins, John; Giglio, Michelle G; Feng, Irene Y; Burns, Gully; Brush, Matthew H; Peters, Bjoern; Stoeckert Jr, Christian J
• Is Part Of: Database. Volume 2021(2021)
• Publication Date: 2021-07-09
• Subjects: Biology -- Databases -- Periodicals; Bioinformatics -- Periodicals; 570.285
• DOI: 10.1093/database/baab040
• Languages: English
• ISSNs: 1758-0463

Abstract

Abstract: The Ontology for Biomedical Investigations (OBI) underwent a focused review of assay term annotations, logic and hierarchy with a goal to improve and standardize these terms. As a result, inconsistencies in W3C Web Ontology Language (OWL) expressions were identified and corrected, and additionally, standardized design patterns and a formalized template to maintain them were developed. We describe here this informative and productive process to describe the specific benefits and obstacles for OBI and the universal lessons for similar projects.