Estimating the preferences and willingness-to-pay for colorectal cancer screening: an opportunity to incorporate the perspective of population at risk into policy development in Thailand. (1st January 2021)

• Record Type: Journal Article
• Authors: Phisalprapa, Pochamana; Ngorsuraches, Surachat; Wanishayakorn, Tanatape; Kositamongkol, Chayanis; Supakankunti, Siripen; Chaiyakunapruk, Nathorn
• Is Part Of: Journal of medical economics. Volume 24:Number 1(2021)
• Page Start: 226
• Page End: 233
• Publication Date: 2021-01-01
• Subjects: Preferences -- willingness-to-pay -- colorectal cancer screening -- discrete choice experiment -- Thailand; Medical care -- Cost control -- Periodicals; Medical economics -- Periodicals; 362.10941
• DOI: 10.1080/13696998.2021.1877145
• Languages: English
• ISSNs: 1369-6998

Abstract

Abstract: Aims: Colorectal cancer (CRC) is one of the public health burdens that can be lowered by early detection. This study aims to examine the preferences and willingness-to-pay of a population at risk for CRC screening in Thailand. Understanding the preferences for these individuals at risk would help Thailand, as an example of LMICs, to design effective population-based CRC screening programs. Materials and methods: A discrete choice experiment (DCE) was conducted among screening-naïve adults aged 50–75 years, who were at risk of CRC, in the out-patient department of a tertiary care hospital in Thailand. A DCE questionnaire was developed from six CRC screening attributes. Each questionnaire was composed of six choice sets and each contained two alternatives described by the different levels of attributes and an opt-out alternative. Participants were asked to choose one alternative from each choice set. A multinomial logit model was developed to determine the relative preference of each attribute. The willingness-to-pays for all attributes and screening modalities and the estimated preferred choices of the annual fecal immunochemical test (FIT), 10-yearly colonoscopy, 5-yearly double-contrast barium enema (DCBE), 5-yearly computed tomographic colonography (CTC), 5-yearly flexible sigmoidoscopy (FS), and no screening was calculated and compared. Results: Four hundred participants were included. All attributes, except pain and less bowel preparation, were statistically associated with the participants' preference ( p < .05). They preferred screenings with a high-risk reduction of CRC-related mortality, no complication, 5-year interval, and lower cost. The estimated preferred choices of FIT, colonoscopy, DCBE, CTC, and FS were 38.2%, 11.4%, 14.6%, 9.2%, and 11.4%, respectively. The willingness-to-pays for each screening modality was US$251, US$189, US$183, US$154, and US$142 (8, 107, 6, 105, 5, 911, 4, 974, and 4, 587 THB) per episode, respectively. Conclusions: The risk reduction of CRC-related mortality, complication, screening interval, and cost influenced the CRC screening preferences of Thai adults. FIT was the most preferred. Policymakers can develop a successful CRC screening campaign using these findings, incorporating the perspective of the population at risk in policy formulation to accomplish their goals.