ACTUARIAL CRITERIA FOR MCI DIAGNOSIS IN ACTIVE: IMPLICATIONS OF ADJUSTMENT FOR RACE. (8th November 2019)

• Record Type: Journal Article
• Authors: Thomas, Kelsey; Cook, Sarah; Unverzagt, Fred; Bondi, Mark W; Marsiske, Michael
• Is Part Of: Innovation in aging. Volume 3(2019)Supplement 1
• Page Start: S432
• Page End: S432
• Publication Date: 2019-11-08
• Subjects: Aging -- Periodicals; Gerontology -- Periodicals; 612.67
• DOI: 10.1093/geroni/igz038.1617
• Languages: English
• ISSNs: 2399-5300

Abstract

Abstract: This study examined the baseline prevalence of mild cognitive impairment (MCI) in the ACTIVE study using actuarial criteria for MCI. Participants (n=2763; 26% Black) were classified as probable MCI cases if they had two observed test scores within the same cognitive domain (memory, reasoning, speed) that were >1SD below a demographically-adjusted expected score (based on the regression weights of a "robust" normal control group). Each score was adjusted using two approaches: Method 1 adjusted for age, sex, and education; Method 2 also adjusted for race. The estimated prevalence of MCI was 33.5% (n=925) in Method 1 and 32.1% (n=887) in Method 2. Adjusting for race reduced the proportion of Black participants classified as probable MCI from 42.3% to 34.9%. Future work will examine whether adjustment for social determinants of health (e.g., education quality, neighborhood/healthcare access) might further improve the utility of this classification method in diverse samples.