Frequency of five cardiovascular/hemostatic entities as primary manifestations of SARS-CoV-2 infection: Results of the UMC-19-S2. (1st May 2021)

• Record Type: Journal Article
• Authors: Miró, Òscar; Llorens, Pere; Jiménez, Sònia; Piñera, Pascual; Burillo-Putze, Guillermo; Martín, Alfonso; Martín-Sánchez, Francisco Javier; González del Castillo, Juan; Miró, Òscar; Jiménez, Sònia; del Castillo, Juan González; Martín-Sánchez, Francisco Javier; Llorens, Pere; Burillo-Putze, Guillermo; Martín, Alfonso; Salmerón, Pascual Piñera; Chaib, Fahd Beddar; del Hoyo Peláez, Enrique; Miranda, Belén Rodríguez; Arias, Alejandra Sánchez; de Lobera, Noemí Ruiz; Vela, Marta Iglesias; López, Laura Hernando; del Arco Galán, Carmen; Jiménez, Guillermo Fernández; Lamberechts, E. Jorge García; Fragiel, Marcos; Domínguez, María Jesús; Ramos, María Eugenia Barrero; Amez, José María Ferreras; Entrala, Belén Arribas; García, Ángel García; de Frutos, Marta Fuentes; López, Ricardo Calvo; Jacob-Rodríguez, Javier; Llopis-Roca, Ferrán; Ponce, María Carmen; Meléndez, Napoleón; Bayarri, María José Fortuny; Suárez, Francisco José Salvador; Grima, María Luisa López; Gómez, Mª. Ángeles Juan; Millán, Javier; Sánchez Nicolás, José A.; Aragües, Paula Lázaro; Lucas-Imbernón, Francisco Javier; Lucas-Galán, Francisco Javier; Jiménez, Blas; Jiménez, Blas; del Río, Rigoberto; García, Lluís LLauger; Espinosa, Begoña; Payá, Ana Belén; Porrino, Juan Miguel; Maestre, María Rosales; Cano, María José Cano; Serra, Rosa Sorando; Cardozo, Carlos; Díaz, Juan José López; Grinspan, Martín Ruiz; Rodríguez Leal, Cristóbal M.; Martín, Sara Gayoso; Zamorano, Silvia Ortiz; Díaz, María Pilar López; Urbano, Carmen Agüera; Padial, Elisa Delgado; Gómez, Ana Peiró; Bellver, Elena Gonzalo; Martínez, Laura Ejarque; Lambíes, Maribel Marzo; Noceda, José; Aznar, José Vicente Brasó; López, José Luis Ruiz; Tejedo, Alfons Aguirre; Lorenzo, Isabel Cirera; Quirós, Alejandro Martín; del Val, Elena Muñoz; Mojarro, Enrique Martín; Jiménez, Brigitte Silvana Alarcón; Carbajosa, Virginia; Ramón, Susana Sánchez; Tejera, Matilde González; Puente, Pablo Herrero; Herrera, Desire María Velarde; Muñoz, Francisco Javier Teigell; González, Juan Carlos Repáraz; Martínez, Félix González; Olmeda, Diana Moya; Palau, Anna; Hernández, Patricia Eiroa; Rodríguez, Marcos Expósito; Laguna, Nieves López; García-Uría, María; Guardiola, Josep; Sansome, Polo Higa; González, María José Marchena; Saavedra, EissaJaloud; Adroher, María; Ferrer, Ester Soy; Huertas, Arturo; Gárate, Raquel Torres; Borrego, Beatriz Valle; MòdolDeltell, Josep María; Soto, Samuel Olmos; Fernández, Elena Díaz; Monzo, José Pavón; González, Nayra Cabrera; Juárez, Ricardo; García, Jorge Pedraza; Salido, Manuel; Fernández, Miguel Moreno; Pérez, Carles; Vera, María Teresa Maza; Calveiro, Raquel Rodríguez; Tost, Josep; Barceló, Antonio; Carrió, Rosario; Moto, Eva Quero;
• Is Part Of: International journal of cardiology. Volume 330(2021)
• Page Start: 268
• Page End: 272
• Publication Date: 2021-05-01
• Subjects: Cardiology -- Periodicals; Electronic journals; 616.12
• DOI: 10.1016/j.ijcard.2021.01.051
• Languages: English
• ISSNs: 0167-5273

Abstract

Highlights: Several cardiovascular/hemostatic disturbances haves been reported in patients with COVID-19, but the real frequency and their potential association with the pathogenic mechanisms of SARS-CoV-19 still remain to be defined. We investigated the relative frequency of acute coronary syndrome, deep venous thrombosis, pulmonary embolism, stroke and upper gastrointestinal bleeding in COVID patents attending emergency departments (EDs), before hospitalization and compared them with frequencies in the general ED population attending 50 Spanish EDs. We found that the risk of pulmonary embolism is clearly increased in COVID patients, with an OR of 4.53 with respect to non-COVID patients (95% confidence interval 4.03- 5.10). Additionally, the diagnosis of pulmonary embolism was 2 fold more frequent among ED comers in 2020 compared to 2019, suggesting a SARS-CoV-2 role in such increment of cases.. The remaining entities studied were not found to be unequivocally increased in the present study and need further investigation.