Dynamic Aphasia as a Variant of Frontotemporal Dementia. Issue 4 (December 2021)

• Record Type: Journal Article
• Authors: Chandregowda, Adithya; Clark, Heather M.; Duffy, Joseph R.; Machulda, Mary M.; Lowe, Val J.; Whitwell, Jennifer L.; Josephs, Keith A.
• Is Part Of: Cognitive and behavioral neurology. Volume 34:Issue 4(2021)
• Publication Date: 2021-12
• Subjects: primary progressive aphasia -- dynamic aphasia -- propositional language -- left frontal lobe -- frontotemporal dementia; Neuropsychiatry -- Periodicals; Clinical neuropsychology -- Periodicals; 616.8005
• DOI: 10.1097/WNN.0000000000000289
• Languages: English
• ISSNs: 1543-3633

Abstract

Abstract : We describe two individuals with progressive verbal difficulty who exhibited impairment of propositional language, with relatively well-preserved auditory comprehension, naming, and repetition—a profile that is consistent with dynamic aphasia. By providing a brief review of pertinent literature and the results from our neurologic, speech and language, neuropsychological, and neuroimaging testing, this report sheds light on the infrequently reported dynamic aphasia in the context of frontotemporal dementia. Our patients' insights into their verbal difficulty tend to support the notion that dynamic aphasia results from interference at the stage where thoughts are converted into verbal messages—that is, the thought–verbal interface.