Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases. (14th August 2019)

• Record Type: Journal Article
• Authors: Priyam, Anurag; Woodcroft, Ben J; Rai, Vivek; Moghul, Ismail; Munagala, Alekhya; Ter, Filip; Chowdhary, Hiten; Pieniak, Iwo; Maynard, Lawrence J; Gibbins, Mark Anthony; Moon, HongKee; Davis-Richardson, Austin; Uludag, Mahmut; Watson-Haigh, Nathan S; Challis, Richard; Nakamura, Hiroyuki; Favreau, Emeline; Gómez, Esteban A; Pluskal, Tomás; Leonard, Guy; Rumpf, Wolfgang; Wurm, Yannick
• Is Part Of: Molecular biology and evolution. Volume 36:Number 12(2019)
• Page Start: 2922
• Page End: 2924
• Publication Date: 2019-08-14
• Subjects: visualization -- BLAST -- comparative genomics -- sequence analysis; Molecular biology -- Periodicals; Molecular evolution -- Periodicals; Evolution, Molecular -- Periodicals; Molecular Biology -- Periodicals; 572.8
• DOI: 10.1093/molbev/msz185
• Languages: English
• ISSNs: 0737-4038

Abstract

Abstract: Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis errors and provides flexible text-based and visual outputs to support researcher productivity. Our software can be rapidly installed for use by individuals or on shared servers.