Case report: Mechanical mitral prosthetic valve thrombosis in the context of COVID-19 despite effective anticoagulation. Issue 2 (24th January 2022)

• Record Type: Journal Article
• Authors: Jeckelmann, Clarisse; Djokic, Bojan; Duchatelle, Valérie; Girod, Grégoire
• Editors: Sinning, Christoph; Pavasini, Rita; Deharo, Pierre; Giampatzis, Vasilios; Baghdasaryan, Lilit; Asher, Elad; Bernstein, Brett Sydney; Chakir, Mariame
• Is Part Of: European heart journal. Volume 6:Issue 2(2022)
• Publication Date: 2022-01-24
• Subjects: Coronavirus -- Mechanical mitral valve thrombosis -- Thrombolysis anticoagulation -- Case report; Cardiology -- Periodicals; Cardiology -- Case studies -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Diseases -- Case studies -- Periodicals; 616.12
• DOI: 10.1093/ehjcr/ytac006
• Languages: English
• ISSNs: 2514-2119

Abstract

Abstract: Background: The SARS-CoV2 virus has been an emerging virus since December 2019 and is the cause of a global pandemic whose clinical manifestations extend far beyond respiratory disease. Case summary: A patient with severe coronavirus disease 2019 respiratory infection, carrying a mechanical mitral valve and under anticoagulation, was admitted to our cardiology department because of a new atrial fibrillation, which turned out to be related to thrombosis of the mitral mechanical valve. Conclusion: The pro-coagulant effect of the SARS-CoV2 virus does not spare patients at risk of thrombosis, even under effective anticoagulation. In patients with mechanical valves under vitamin K antagonist treatment, there is a high risk of thrombus formation. The treatment is based on thrombolysis by therapeutic anticoagulation, fibrinolysis, or surgery depending on the size, composition of thrombus, and clinical manifestation.