Identification of the gene encoding 3-(5-oxo-2-thioxoimidazolidin-4-yl) propionic acid desulfhydrase in Burkholderia sp. HME13. Issue 3 (31st December 2020)

• Record Type: Journal Article
• Authors: Muramatsu, Hisashi; Maguchi, Hiroki; Harada, Taisuke; Kashiwagi, Takehiro; Kim, Chul-Sa; Kato, Shin-ichiro; Nagata, Shinji
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 85:Issue 3(2021)
• Page Start: 626
• Page End: 629
• Publication Date: 2020-12-31
• Subjects: ergothioneine -- 3-(5-oxo-2-thioxoimidazolidin-4-yl) propionic acid desulfhydrase -- 3-(2, 5-dioxoimidazolidin-4-yl) propionic acid -- Burkholderia; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1093/bbb/zbaa066
• Languages: English
• ISSNs: 0916-8451

Abstract

ABSTRACT: Here, we report the identification of the gene encoding a novel enzyme, 3-(5-oxo-2-thioxoimidazolidin-4-yl) propionic acid desulfhydrase, in Burkholderia sp. HME13. The enzyme converts 3-(5-oxo-2-thioxoimidazolidin-4-yl) propionic acid and H2 O to 3-(2, 5-dioxoimidazolidin-4-yl) propionic acid and H2 S. Amino acid sequence analysis of the enzyme indicates that it belongs to the DUF917 protein family, which consists of proteins of unknown function.