Effects of Rehabilitation Program on Quality of Life, Sleep, Rest-Activity Rhythms, Anxiety, and Depression of Patients With Esophageal Cancer: A Pilot Randomized Controlled Trial. Issue 2 (1st March 2022)

• Record Type: Journal Article
• Authors: Chen, Hui-Mei; Lin, Yi-Yun; Wu, Yu-Chung; Huang, Chien-Sheng; Hsu, Po-Kuei; Chien, Ling-I; Lin, Yu-Jung; Huang, Hsiu-Li
• Is Part Of: Cancer nursing. Volume 45:Issue 2(2022)
• Page Start: E582
• Page End: E593
• Publication Date: 2022-03-01
• Subjects: Anxiety -- Depression -- Esophageal cancer -- Exercise -- Quality of life -- Rest-activity rhythms -- Sleep quality; Cancer -- Nursing -- Periodicals; 610.736
• DOI: 10.1097/NCC.0000000000000953
• Languages: English
• ISSNs: 0162-220X

Abstract

Abstract : Background: Esophageal cancer patients experience severe symptoms and poor quality of life. Objective: We examined the effects of a rehabilitation program on quality of life, sleep, rest-activity rhythms, anxiety, and depression of esophageal cancer patients. Methods: Forty-four patients with esophageal cancer were randomly assigned to an experimental group, which underwent a 12-week brisk walking and diet education program, or a control group, which received standard care. Health-related quality of life, subjective and objective sleep quality, rest-activity rhythms, anxiety, and depression were assessed at baseline and post intervention. Results: A generalized estimating equation analysis revealed that, after intervention, compared with the control group, the experimental group exhibited significantly improved reflux ( P = .022; effect size, 0.32) and marginally improved emotional ( P = .069; effect size, 0.27) and social ( P = .069; effect size, 0.27) functions; constipation ( P = .050; effect size, 0.29), eating difficulty ( P = .058; effect size, 0.27), anxiety ( P = .050; effect size, 0.29), and total sleep time ( P = .068; effect size, 0.39). Conclusions: The rehabilitation program may improve health-related quality of life and sleep and alleviate anxiety in patients with esophageal cancer. Implications for Practice: A rehabilitation program comprising exercise and diet education is a feasible and low-cost intervention for improving quality of life of patients with esophageal cancer. Healthcare team members may consider it as a nonpharmacological treatment option for patients.