Antiretroviral Prophylaxis: A Digestive Complication to Know. Issue 12 (December 2021) - Lemoine, Anaïs
Abstract : Abstract: An 8-year-old child experienced abdominal pain and melena due to duodenal and ileal ulcerations throughout antiretroviral prophylactic treatment after a needlestick injury. Mild to moderate adverse effects often occur with lamivudine and zidovudine, but more severe adverse effects such as intestinal ulcers resulting in melena after a prophylactic antiretroviral treatment may question the safety of the current guidelines.