Customized valorization of waste streams by Pseudomonas putida: State-of-the-art, challenges, and future trends. (March 2023)

• Record Type: Journal Article
• Authors: Son, Jina; Lim, Seo Hyun; Kim, Yu Jin; Lim, Hye Jin; Lee, Ji Yeon; Jeong, Seona; Park, Chulhwan; Park, Si Jae
• Is Part Of: Bioresource technology. Volume 371(2023)
• Publication Date: 2023-03
• Subjects: Waste management -- Pseudomonas putida -- Cis, cis-Muconic acid -- Adipic acid -- Mcl-PHA; Biomass -- Periodicals; Biomass energy -- Periodicals; Bioremediation -- Periodicals; Agricultural wastes -- Periodicals; Factory and trade waste -- Periodicals; Organic wastes -- Periodicals; Bioénergie -- Périodiques; Déchets agricoles -- Périodiques; Déchets industriels -- Périodiques; Déchets organiques -- Périodiques; Déchets (Combustible) -- Périodiques; 662.88
• DOI: 10.1016/j.biortech.2023.128607
• Languages: English
• ISSNs: 0960-8524

Abstract

Graphical abstract: Highlights: Possibility of converting industrial waste into valuable products is explored. Streamlined model Pseudomonas putida strains enable successful waste management. MA, AA, and mcl -PHA were successfully bio-manufactured from waste. Directions for developing P. putida as a synthetic biology tool are proposed. Abstract: Preventing catastrophic climate events warrants prompt action to delay global warming, which threatens health and food security. In this context, waste management using engineered microbes has emerged as a long-term eco-friendly solution for addressing the global climate crisis and transitioning to clean energy. Notably, Pseudomonas putida can valorize industry-derived synthetic wastes including plastics, oils, food, and agricultural waste into products of interest, and it has been extensively explored for establishing a fully circular bioeconomy through the conversion of waste into bio-based products, including platform chemicals (e.g., cis, cis -muconic and adipic acid) and biopolymers (e.g., medium-chain length polyhydroxyalkanoate). However, the efficiency of waste pretreatment technologies, capability of microbial cell factories, and practicability of synthetic biology tools remain low, posing a challenge to the industrial application of P. putida . The present review discusses the state-of-the-art, challenges, and future prospects for divergent biosynthesis of versatile products from waste-derived feedstocks using P. putida .