OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY EVALUATION OF PERIPAPILLARY MICROVASCULAR CHANGES AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR. Issue 12 (December 2021)

• Record Type: Journal Article
• Authors: Bonfiglio, Vincenza; Ortisi, Elina; Nebbioso, Marcella; Reibaldi, Michele; Lupidi, Marco; Russo, Andrea; Fallico, Matteo; Scollo, Davide; Macchi, Iacopo; Pizzo, Alessandra; Panebianco, Roberta; Patanè, Clara; Vadalà, Maria; Toro, Mario D.; Rejdak, Robert; Nowomiejska, Katarzyna; Avitabile, Teresio; Longo, Antonio
• Is Part Of: Retina. Volume 41:Issue 12(2021)
• Publication Date: 2021-12
• Subjects: radial peripapillary capillary plexus -- OCT-angiography -- retinal nerve fiber layer -- retinal detachment; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000003253
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : Purpose: To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. Methods: In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the corresponding areas of the healthy fellow eyes (control group). Results: Fifty-three eyes were included in the study. A significantly lower RPCP VD and RNFL thickness were observed in those subfields affected by rhegmatogenous retinal detachment compared with those of the control group ( P < 0.001). No statistically significant differences were observed between undetached subfields in the study group and their corresponding images in the control group. In the study group, a significant correlation was found between RPCP VD and RNFL thickness in subfields with detached retina (r = 0.393, P < 0.001) and undetached retina (r = 0.321, P < 0.001). Conclusion: Radial peripapillary capillary plexus VD changes were found in the subfields of detached retina successfully treated with pars plana vitrectomy and they correlated with RNFL thinning. These data suggest a coexistence of neuronal and microvascular damage in patients affected by rhegmatogenous retinal detachment. Abstract : The reductions of radial peripapillary capillary plexus vessel density and retinal nerve fiber layer thickness in detached subfields of rhegmatogenous retinal detachment eyes successfully treated by vitrectomy suggest a coexistence of neuronal and microvascular damage.