Trichomoniasis refractory to 5-nitroimidazole therapy in Trinidad. (January 2023)

• Record Type: Journal Article
• Authors: Edwards, Robert Jeffrey; Parboo, Miriam; Edwards, Jonathan; Boyce, Gregory
• Is Part Of: Tropical doctor. Volume 53:Number 1(2023)
• Page Start: 143
• Page End: 145
• Publication Date: 2023-01
• Subjects: Trichomoniasis -- refractory -- 5-nitroimidazole -- boric acid -- clotrimazole; Tropical medicine -- Periodicals; Medical care -- Developing countries -- Periodicals; Developing Countries -- Periodicals; Tropical Medicine -- Periodicals; Tropische geneeskunde; 616.9883
• DOI: 10.1177/00494755221131370
• Languages: English
• ISSNs: 0049-4755

Abstract

Trichomoniasis is the most common non-viral sexually transmitted infection (STI) occurring worldwide and the majority of infected persons (70–85%) have mild or no genital symptoms. Symptoms in women may include a vaginal discharge which may be associated with vulval irritation and most infections can be effectively treated with metronidazole 500mg bd for seven days. Trichomoniasis unresponsive to 5-nitroimidazole therapy is uncommon but results in substantial therapeutic challenges, especially in resource limited countries. We present such a case which was eventually treated with a low-cost intravaginal combination of boric acid and clotrimazole cream.