Association between residential greenness and cognitive function: analysis of the Chinese Longitudinal Healthy Longevity Survey. Issue 2 (26th August 2019)

• Record Type: Journal Article
• Authors: Zhu, Anna; Wu, Chenkai; Yan, Lijing L; Wu, Chih-Da; Bai, Chen; Shi, Xiaoming; Zeng, Yi; Ji, John S
• Is Part Of: BMJ nutrition, prevention & health. Volume 2:Issue 2(2019)
• Page Start: 72
• Page End: 79
• Publication Date: 2019-08-26
• Subjects: residential greenness -- Normalised Difference Vegetation Index -- cognitive function -- Mini-Mental State Examination (MMSE) -- China -- ageing -- environmental epidemiology; Nutrition -- Periodicals; Health behavior -- Periodicals; Lifestyles -- Periodicals; 613
• DOI: 10.1136/bmjnph-2019-000030
• Languages: English
• ISSNs: 2516-5542

Abstract

Abstract : Introduction: Proximity to vegetated green space has been linked to better physical and mental health. However, the relationship between residential greenness and cognitive function and its decline among older adults is not clear in large cohort studies. Methods: Our study used the 2000, 2002, 2005, 2008 and 2011 wave of the Chinese Longitudinal Healthy Longevity Survey. We calculated the Normalised Difference Vegetation Index (NDVI) using a 500 m radius around participants' residential addresses. Mini-Mental State Examination (MMSE) was applied to measure cognitive function. Our study included the cross-sectional analysis using the linear regression, and logistical regression, and also the longitudinal analysis using the linear mixed effects regression, and mixed effects logistic regression. Our study also conducted a sensitivity analysis using the survey-weighted regression. Additionally, our study participants were categorised into those living in areas of positive and negative changes in NDVI in relation to MMSE. All regression models were adjusted for a range of covariates. Results: Among 38 327 participants at baseline, the mean MMSE score was 21. Annual average NDVI ranged from −0.11 to 0.76. In the cross-sectional analysis, each 0.1-unit increase in NDVI was associated with a 0.23-point increase in MMSE score (95% CI 0.16 to 0.29) in the linear regression, and an OR of 0.94 (95% CI 0.92 to 0.96) of having cognition impairment in the logistic regression. In the second analysis, looking at changes in NDVI and MMSE score, compared with the participants living in areas with an increase in NDVI, those living in areas with a decrease in greenness had an OR of 1.25 (95% CI 1.18 to 1.34) of a decrease in MMSE, and an OR of 0.90 (95% CI 0.84 to 0.96) of an increase in MMSE. In the longitudinal analysis, we found a significantly weak association (coefficient 0.069, 95% CI 0.0048 to 0.13) in the linear mixed effects regression, but not in the mixed effects logistic regression. Conclusion: We found evidence of an association between higher residential greenness and better cognitive function among older adults. Our finding provides insight into neurodegeneration and has implications for preventing dementia and Alzheimer's disease in China.